What exactly is meant when Alzheimer’s disease is referred to as Type 3 diabetes? Amy Berger answers this question in her book The Alzheimer’s Antidote where she has synthesized what we know about Alzheimer’s disease (AD) to lead us closer to the cause: a fuel shortage in the brain. How and why this occurs is explained in the book, with dietary and lifestyle changes to counteract the process.
Metabolic syndrome is a known risk factor for AD. Insulin resistance is a factor in both and causes higher blood levels of insulin (hyperinsulinemia). Glucose is the brain’s primary source of fuel. A marker for Alzheimer’s disease is a reduction in the rate of glucose metabolized by the brain. In some, the reduction has been found to be 45 percent and is always localized to areas of the brain involved with learning and memory. As the brain cells become less able to metabolize glucose for fuel, they starve. Berger notes that some researchers have found this to be the predominant abnormality in AD.